The Gamma-Glutamyl Transferase (GGT) Test is a blood test that measures an enzyme present mainly in the liver and bile ducts. Elevated GGT levels may indicate liver or bile duct problems, although other factors can also affect the result.
GGT is commonly performed as part of an evaluation of abnormal liver enzyme results and can help healthcare professionals investigate the source of elevated alkaline phosphatase (ALP).
What Does the GGT Test Help Assess?
- Liver Health: Helps investigate possible liver injury.
- Bile Duct Conditions: May support the assessment of impaired bile flow.
- Abnormal ALP Results: Helps determine whether elevated ALP may be related to the liver or bile ducts.
- Treatment Monitoring: May be used to monitor selected liver-related conditions.
Sample Requirements
- Sample type: Blood, typically serum.
- Fasting: Your doctor or laboratory may request fasting, depending on the testing protocol.
- Preparation: Inform your healthcare professional about medicines, supplements, and alcohol consumption, as these may affect results.
Understanding Your Results
Elevated GGT levels may occur with liver disease, bile duct disorders, alcohol exposure, and certain medication effects. GGT is sensitive but not specific to one disease, so an elevated result does not establish a diagnosis.
Your healthcare professional may interpret GGT alongside SGOT (AST), SGPT (ALT), ALP, bilirubin, symptoms, and medical history.
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